My research focuses on the different aspects of schizophrenia and other psychotic disorders. I have conducted extensive research using non-invasive brain stimulation to evaluate cortical excitability, connectivity and plasticity at different stages of schizophrenia. Furthermore, I have investigated and developed new paradigms to induce cortical plasticity in humans, laying the foundation for new treatment tools in psychotic disorders. One major interest is to understand the inter-individual variability in the response to various types of brain stimulation.
I have been involved in the implementation and analyses of the largest, multi-center, randomized-controlled trial to investigate the efficacy of non-invasive brain stimulation in the treatment of schizophrenia. Beyond my interests in human physiology, I am particularly interested in evidence-based psychiatry and guideline-development. I am first author of the new WFSBP guidelines for the biological treatment of schizophrenia and I am a member of the review board of the German guidelines for schizophrenia.