Publications of Janine Arloth

Journal Article (19)

2024
Journal Article
Arcego, D. M.; Buschdorf, J.-P.; O'Toole, N.; Wang, Z.; Barth, B.; Pokhvisneva, I.; Rayan, N. A.; Patel, S.; de Mendonca Filho, E. J.; Lee, P. et al.; Tan, J.; Koh, M. X.; Sim, C. M.; Parent, C.; de Lima, R. M. S.; Clappison, A.; O'Donnell, K. J.; Dalmaz, C.; Arloth, J.; Provencal, N.; Binder, E. B.; Diorio, J.; Silveira, P. P.; Meaney, M. J.: A Glucocorticoid-Sensitive Hippocampal Gene Network Moderates the Impact of Early-Life Adversity on Mental Health Outcomes. BIOLOGICAL PSYCHIATRY 95 (1), pp. 48 - 61 (2024)
2023
Journal Article
Kuehnel, A.; Hagenberg, J.; Knauer-Arloth, J.; Koedel, M.; Czisch, M.; Saemann, P. G.; Binder, E. B.; Kroemer, N. B.: Stress-induced brain responses are associated with BMI in women. COMMUNICATIONS BIOLOGY 6 (1), 1031 (2023)
Journal Article
Matosin, N.; Arloth, J.; Czamara, D.; Edmond, K. Z.; Maitra, M.; Froehlich, A. S.; Martinelli, S.; Kaul, D.; Bartlett, R.; Curry, A. R. et al.; Gassen, N. C.; Hafner, K.; Mueller, N. S.; Worf, K.; Rehawi, G.; Nagy, C.; Halldorsdottir, T.; Cruceanu, C.; Gagliardi, M.; Gerstner, N.; Ködel, M.; Murek, V.; Ziller, M. J.; Scarr, E.; Tao, R.; Jaffe, A. E.; Arzberger, T.; Falkai, P.; Kleinmann, J. E.; Weinberger, D. R.; Mechawar, N.; Schmitt, A.; Dean, B.; Turecki, G.; Hyde, T. M.; Binder, E. B.: Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 145 (4), pp. 439 - 459 (2023)
Journal Article
Penner-Goeke, S.; Bothe, M.; Rek, N.; Kreitmaier, P.; Poehlchen, D.; Kühnel, A.; Glaser, L. V.; Kaya, E.; Krontira, A.; Roeh, S. et al.; Czamara, D.; Ködel, M.; Monteserin-Garcia, J.; Diener, L.; Woelfel, B.; Sauer, S.; Rummel, C.; Riesenberg, S.; Arloth-Knauer, J.; Ziller, M.; Labeur, M.; Meijsing, S.; Binder, E. B.: High- throughput screening of glucocorticoid- induced enhancer activity reveals mechanisms of stress- related psychiatric disorders. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (49), e2305773120 (2023)
2022
Journal Article
Czamara, D.; Neufang, A.; Dieterle, R.; Iurato, S.; Arloth, J.; Martins, J.; Ising, M.; Binder, E. B.; Erhardt, A.: Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder. CLINICAL EPIGENETICS 14 (1), 55 (2022)
Journal Article
Cruceanu, C.; Dony, L.; Krontira, A. C.; Fischer, D. S.; Roeh, S.; Di Giaimo, R.; Kyrousi, C.; Kaspar, L.; Arloth, J.; Czamara, D. et al.; Gerstner, N.; Martinelli, S.; Wehner, S.; Breen, M. S.; Koedel, M.; Sauer, S.; Sportelli, V.; Rex-Haffner, M.; Cappello, S.; Theis, F. J.; Binder, E. B.: Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. AMERICAN JOURNAL OF PSYCHIATRY 179 (5), pp. 375 - 387 (2022)
Journal Article
Gerstner, N.; Krontira, A. C.; Cruceanu, C.; Roeh, S.; Puetz, B.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.; Knauer-Arloth, J.: DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions. NEUROBIOLOGY OF STRESS 21, 100496 (2022)
2021
Journal Article
Kappelmann, N.; Arloth, J.; Georgakis, M. K.; Czamara, D.; Rost, N.; Ligthart, S.; Khandaker, G. M.; Binder, E. B.: Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms A Genetic Correlation and 2-Sample Mendelian Randomization Study. JAMA PSYCHIATRY 78 (2), pp. 161 - 170 (2021)
Journal Article
Kappelmann, N.; Czamara, D.; Rost, N.; Moser, S.; Schmoll, V.; Trastulla, L.; Stochl, J.; Lucae, S.; Binder, E. B.; Khandaker, G. M. et al.; Arloth, J.: Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study. BRAIN BEHAVIOR AND IMMUNITY 95, pp. 256 - 268 (2021)
Journal Article
Moore, S. R.; Halldorsdottir, T.; Martins, J.; Lucae, S.; Mueller-Myhsok, B.; Mueller, N. S.; Piechaczek, C.; Feldmann, L.; Freisleder, F. J.; Greimel, E. et al.; Schulte-Koerne, G.; Binder, E. B.; Arloth, J.: Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation. TRANSLATIONAL PSYCHIATRY 11 (1), 632 (2021)
Journal Article
Ogris, C.; Hu, Y.; Arloth, J.; Mueller, N. S.: Versatile knowledge guided network inference method for prioritizing key regulatory factors in multi-omics data. SCIENTIFIC REPORTS 11 (1), 6806 (2021)
2020
Journal Article
Arloth, J.; Eraslan, G.; Andlauer, T. F. M.; Martins, J.; Iurato, S.; Kuehnel, B.; Waldenberger, M.; Frank, J.; Gold, R.; Hemmer, B. et al.; Luessi, F.; Nischwitz, S.; Paul, F.; Wiendl, H.; Gieger, C.; Heilmann-Heimbach, S.; Kacprowski, T.; Laudes, M.; Meitinger, T.; Peters, A.; Rawal, R.; Strauch, K.; Lucae, S.; Müller-Myhsok, B.; Rietschel, M.; Theis, F. J.; Binder, E. B.; Mueller, N. S.: DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning. PLOS COMPUTATIONAL BIOLOGY 16 (2), e1007616 (2020)
Journal Article
Provencal, N.; Arloth, J.; Cattaneo, A.; Anacker, C.; Cattane, N.; Wiechmann, T.; Roeh, S.; Koedel, M.; Klengel, T.; Czamara, D. et al.; Mueller, N. S.; Lahti, J.; Raikkonen, K.; Pariante, C. M.; Binder, E. B.: Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (38), pp. 23280 - 23285 (2020)
2019
Journal Article
Elbau, I.; Brucklmeier, B.; Uhr, M.; Arloth, J.; Czamara, D.; Spoormaker, V.; Czisch, M.; Stephan, K. E.; Binder, E. B.; Saemann, P. G.: A polygenic score of molecular sensitivity to GR-stimulation maps to stress related changes of the brains hemodynamic response function. JOURNAL OF NEURAL TRANSMISSION 126 (11), p. 1559 - 1559 (2019)
Journal Article
Elbau, I.; Bruecklmeier, B.; Uhr, M.; Arloth, J.; Czamara, D.; Spoormaker, V.; Czisch, M.; Stephan, K. E.; Binder, E. B.; Saemann, P. G.: A polygenic score of molecular sensitivity to GR-stimulation maps to stress related changes of the brains hemodynamic response function. JOURNAL OF NEURAL TRANSMISSION 126 (11), pp. 1519 - 1520 (2019)
Journal Article
Wiechmann, T.; Roeh, S.; Sauer, S.; Czamara, D.; Arloth, J.; Koedel, M.; Beintner, M.; Knop, L.; Menke, A.; Binder, E. B. et al.; Provencal, N.: Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. CLINICAL EPIGENETICS 11, 83 (2019)
Journal Article
Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23), pp. 11370 - 11379 (2019)
Journal Article
Zimmermann, C. A.; Arloth, J.; Santarelli, S.; Loeschner, A.; Weber, P.; Schmidt, M. V.; Spengler, D.; Binder, E. B.: Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes. TRANSLATIONAL PSYCHIATRY 9, 41 (2019)
2018
Journal Article
Engel, M.; Eggert, C.; Kaplick, P. M.; Eder, M.; Röh, S.; Tietze, L.; Namendorf, C.; Arloth, J.; Weber, P.; Rex-Haffner, M. et al.; Geula, S.; Jakovcevski, M.; Hanna, J. H.; Leshkowitz, D.; Uhr, M.; Wotjak, C. T.; Schmidt, M. V.; Deussing, J. M.; Binder, E. B.; Chen, A.: The Role of m6A/m-RNA Methylation in Stress Response Regulation. NEURON 99 (2), pp. 389 - 403 (2018)

Meeting Abstract (3)

2023
Meeting Abstract
Froehlich, A. S.; Gerstner, N.; Gagliardi, M.; Ködel, M.; Matosin, N.; Yusupov, N.; Murek, V.; Czamara, D.; Roeh, S.; Arloth, J. et al.; Ziller, M. J.; Binder, E. B.: CELL-TYPE SPECIFIC AGEING EFFECTS IN THE HUMAN ORBITOFRONTAL CORTEX AND IMPLICATIONS FOR PSYCHIATRIC DISEASE. In EUROPEAN NEUROPSYCHOPHARMACOLOGY, 75, pp. S25 - S26. World Congress of Psychiatric Genetics (WCPG), Montreal, CANADA, October 10, 2023 - October 14, 2023. (2023)
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