Publications of Nils C. Gassen

Journal Article (15)

2022
Journal Article
Budzinski, M. L.; Sokn, C.; Gobbini, R.; Ugo, B.; Antunica-Noguerol, M.; Senin, S.; Bajaj, T.; Gassen, N. C.; Rein, T.; Schmidt, M. V. et al.; Binder, E. B.; Arzt, E.; Liberman, A. C.: Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity. MOLECULAR PSYCHIATRY (2022)
Journal Article
Hausl, A. S.; Bajaj, T.; Brix, L.; Pohlmann, M. L.; Hafner, K.; De Angelis, M.; Nagler, J.; Dethloff, F.; Balsevich, G.; Schramm, K.-W. et al.; Giavalisco, P.; Chen, A.; Schmidt, M. V.; Gassen, N. C.: Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism. SCIENCE ADVANCES 8 (10), eabi4797 (2022)
2021
Journal Article
Hausl, A. S.; Brix, L.; Hartmann, J.; Poehlmann, M. L.; Lopez, J. P.; Menegaz, D.; Brivio, E.; Engelhardt, C.; Roeh, S.; Bajaj, T. et al.; Rudolph, L.; Stoffel, R.; Hafner, K.; Goss, H. M.; Reul, J. M. H. M.; Deussing, J. M.; Eder, M.; Ressler, K. J.; Gassen, N. C.; Chen, A.; Schmidt, M. V.: The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY (2021)
Journal Article
Ebert, T.; Heinz, D. E.; Almeida-Correa, S.; Cruz, R.; Dethloff, F.; Stark, T.; Bajaj, T.; Maurel, O. M.; Ribeiro, F. M.; Calcagnini, S. et al.; Hafner, K.; Gassen, N. C.; Turck, C. W.; Boulat, B.; Czisch, M.; Wotjak, C. T.: Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice. FRONTIERS IN AGING NEUROSCIENCE 13, 731603 (2021)
Journal Article
Herrmann, L.; Ebert, T.; Rosen, H.; Novak, B.; Philipsen, A.; Touma, C.; Schreckenbach, M.; Gassen, N. C.; Rein, T.; Schmidt, U.: Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans. NEUROBIOLOGY OF STRESS 15, 100401 (2021)
Journal Article
Martinelli, S.; Anderzhanova, E.; Bajaj, T.; Wiechmann, S.; Dethloff, F.; Weckmann, K.; Heinz, D. E.; Ebert, T.; Hartmann, J.; Geiger, T. M. et al.; Doengi, M.; Hafner, K.; Poehlmann, M. L.; Jollans, L.; Philipsen, A.; Schmidt, S. V.; Schmidt, U.; Maccarrone, G.; Stein, V.; Hausch, F.; Turck, C. W.; Schmidt, M. V.; Gellner, A.-K.; Kuster, B.; Gassen, N. C.: Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. NATURE COMMUNICATIONS 12 (1), 4643 (2021)
Journal Article
Moosecker, S.; Pissioti, A.; Leidmaa, E.; Harb, M. R.; Dioli, C.; Gassen, N. C.; Yu, S.; Gazea, M.; Catania, C.; Anderzhanova, E. et al.; Patchev, A. V.; Kuhne, C.; Stoffel, R.; Sotiropoulos, I.; Almeida, O. F. X.: Brain Expression, Physiological Regulation and Role in Motivation and Associative Learning of Peroxisome Proliferator-activated Receptor y. NEUROSCIENCE 479, pp. 91 - 106 (2021)
Journal Article
Schraut, K.-G.; Kalnytska, O.; Lamp, D.; Jastroch, M.; Eder, M.; Hausch, F.; Gassen, N. C.; Moore, S.; Nagaraj, N.; Lopez, J. P. et al.; Chen, A.; Schmidt, M. V.: Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons. EUROPEAN JOURNAL OF NEUROSCIENCE 53 (2), pp. 390 - 401 (2021)
2020
Journal Article
Leidmaa, E.; Gazea, M.; Patchev, A. V.; Pissioti, A.; Gassen, N. C.; Kimura, M.; Liposits, Z.; Kallo, I.; Almeida, O. F. X.: Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus. ACTA PHYSIOLOGICA 228 (2), e13345 (2020)
Journal Article
Leidmaa, E.; Gazea, M.; Patchev, A. V.; Pissioti, A.; Gassen, N. C.; Kimura, M.; Liposits, Z.; Kallo, I.; Almeida, O. F. X.: Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus. ACTA PHYSIOLOGICA 228 (2), e13345 (2020)
2019
Journal Article
Gassen, N. C.; Niemeyer, D.; Muth, D.; Corman, V. M.; Martinelli, S.; Gassen, A.; Hafner, K.; Papies, J.; Moesbauer, K.; Zellner, A. et al.; Zannas, A. S.; Herrmann, A.; Holsboer, F.; Brack-Werner, R.; Boshart, M.; Mueller-Myhsok, B.; Drosten, C.; Mueller, M. A.; Rein, T.: SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS 10, 5770 (2019)
Journal Article
Haeusl, A. S.; Balsevich, G.; Gassen, N. C.; Schmidt, M. V.: Focus on FKBP51: A molecular link between stress and metabolic disorders. Molecular Metabolism 29, pp. 170 - 181 (2019)
Journal Article
Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. Proceedings of the National Academy of Sciences of the United States of America 116 (23), pp. 11370 - 11379 (2019)
Journal Article
Gassen, N. C.; Niemeyer, D.; Muth, D.; Corman, V. M.; Martinelli, S.; Gassen, A.; Hafner, K.; Papies, J.; Moesbauer, K.; Zellner, A. et al.; Zannas, A. S.; Herrmann, A.; Holsboer, F.; Brack-Werner, R.; Boshart, M.; Mueller-Myhsok, B.; Drosten, C.; Mueller, M. A.; Rein, T.: SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS 10, 5770 (2019)
Journal Article
Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23), pp. 11370 - 11379 (2019)

Meeting Abstract (1)

2019
Meeting Abstract
Martinelli, S.; Wiechmann, T.; Kathrin, H.; Meinhold, L.; Roeh, S.; Sauer, S.; Gassen, N.; Binder, E. B.: Unravelling the differential role of FKBP51 (FK506 Binding Protein 5) isoforms in different cellular pathways. In European Neuropsychopharmacology, 29, pp. S652 - S653. ECNP Workshop on Early Career Scientists in Europe, Nice, FRANCE, March 07, 2019 - March 10, 2019. Elsevier, Amsterdam (2019)

Book Review (2)

2019
Book Review
Gassen, N. C.; Rein, T.: Is There a Role of Autophagy in Depression and Antidepressant Action? FRONTIERS IN PSYCHIATRY 10, 337 (2019)
Book Review
Häusl, A. S.; Balsevich, G.; Gassen, N. C.; Schmidt, M. V.: Focus on FKBP51: A molecular link between stress and metabolic disorders. MOLECULAR METABOLISM 29, pp. 170 - 181 (2019)

Editorial (1)

2022
Editorial
Bajaj, T.; Haeusl, A. S.; Schmidt, M. V.; Gassen, N. C.: FKBP5/FKBP51 on weight watch: central FKBP5 links regulatory WIPI protein networks to autophagy and metabolic control. AUTOPHAGY (2022)
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