Below you will find a selection of research articles published by members of the IMPRS-TP faculty prior to September 2016. Please click on the article title to access the repsective Pubmed entry.

Hasan A, Misewitsch K, Nitsche MA, Gruber O, Padberg F, Falkai P, Wobrock T: Impaired Motor Cortex Responses in Non-Psychotic First-Degree Relatives of Schizophrenia Patients: A Cathodal tDCS Pilot Study. Brain Stimulation, 2013 Sep; 6(5):821-9

Hasan A, Wobrock T, Grefkes C, Labusga M, Levold K, Schneider-Axmann T, Falkai P, Müller H, Klosterkötter J, Bechdolf A (2012): Deficient Inhibitory Cortical Networks in Antipsychotic-Naive Subjects at Risk of Developing First-Episode Psychosis and First-Episode Schizophrenia Patients: A Cross-Sectional Study. Biological Psychiatry 2012 Nov1; 72(9):744-51

Koutsouleris N, Meisenzahl EM, Borgwardt S, Riecher-Rössler A, Frodl T, Kambeitz J, Köhler Y, Falkai P, Möller HJ, Reiser M, Davatzikos CIndividualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers. Brain. 2015 Jul;138(Pt 7):2059-73. 

Kambeitz J, Kambeitz-Ilankovic L, Leucht S, Wood S, Davatzikos C, Malchow B, Falkai P, Koutsouleris N.Detecting neuroimaging biomarkers for schizophrenia: a meta-analysis of multivariate pattern recognition studies. Neuropsychopharmacology 2015 Jun;40(7):1742-51

Koutsouleris N, Riecher-Rössler A, Meisenzahl EM, Smieskova R, Studerus E, Kambeitz-Ilankovic L, von Saldern S, Cabral C, Reiser M, Falkai P, Borgwardt S.. Detecting the psychosis prodrome across high-risk populations using neuroanatomical biomarkers. Schizophr Bull. 2015 Mar;41(2):471-82.

Kambeitz-Ilankovic L, Meisenzahl EM, Cabral C, von Saldern S, Kambeitz J, Falkai P, Möller HJ, Reiser M, Koutsouleris NPrediction of outcome in the psychosis prodrome using neuroanatomical pattern classification. Schizophr Res. 2015 Mar 26. pii: S0920-9964(15)00134-6.

original
Circuit function in the CNS relies critically on the balance of excitation and inhibition. In this issue, Mende et al. (pages 1189–1202,Mende et al., 2016, Neuron 90, 1–14 June 15, 2016) use the mouse spinal reflex circuit to propose a model in which coordinated activity-dependent retrograde signals direct the molecular differentiation of axo-axonically synapsing GABAergic terminals. In this model, the inhibitory potency of GABAergic interneurons is increased in response to excitatory activity, such that a homeostatic balance of excitation and inhibition is maintained. The cover image depicts a girl on a tightrope, representing the fine balance both required for, and allowed by, functioning proprioceptive reflex circuits. Cover artwork by Ryuji Yamashita.

Mende M, Fletcher EV, Belluardo JL et al. Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron June 15, 2016: vol90/6, p1189–1202

Andlauer TFM, … Binder EB, ... and Müller-Myhsok BNovel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Sci Adv 2016 (June 17), 2.

Brenndörfer J, Altmann A, Widner-Andrä R, Pütz B, Czamara D, Tilch E, Kam-Thong T, Weber P, Rex-Haffner M, Bettecken T, Bultmann A, Müller-Myhsok B, Binder EE, Landgraf R, Czibere L. Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice. PLoS One. 2015 May 26;10(5):e0128465.

Uher R, Ripke S, Müller-Myhsok B, Lewis CM, Perlis RH. Association of a brain methylation site with clinical outcomes in depression does not replicate across populations. Am J Psychiatry. 2015 Apr;172(4):395-7.

Palm U, Keeser D, Hasan A, ...Falkai P, ..., and Padberg FPrefrontal Transcranial Direct Current Stimulation for Treatment of Schizophrenia With Predominant Negative Symptoms: A Double-Blind, Sham-Controlled Proof-of-Concept StudySchizophr Bull. 2016 Apr 20. pii: sbw041

Jobst A, Brakemeier E-L, ...Falkai P, ....and Padberg FEuropean Psychiatric Association Guidance on psychotherapy in chronic depression across Europe. European Psychiatry 2016, 33: 18–36 

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