Previous Faculty Publications

Below you will find a selection of research articles published by members of the IMPRS-TP faculty prior to 2022.

Vogl AM, Brockmann MM, Giusti SA, Maccarrone G, Vercelli CA, Bauder CA, Richter JS, Roselli F, Hafner AS, Dedic N, Wotjak CT, Vogt-Weisenhorn DM, Choquet D, Turck CW, Stein V, Deussing JM, Refojo D.. Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition. Nat Neurosci. 2015 Feb;18(2):239-51

Protein-protein interactions as illustrated by Erin Boyle on the cover feature of Nature Methods 2006 Vol 3/12.

© Nat Meth 2006

Protein-protein interactions as illustrated by Erin Boyle on the cover feature of Nature Methods 2006 Vol 3/12.

© Nat Meth 2006

Wintgens JP, Rossner MJ, Wehr MC. Characterizing Dynamic Protein-Protein Interactions Using the Genetically Encoded Split Biosensor Assay Technique Split TEV. Methods Mol Biol. 2017;1596:219-238

Wehr MC and Rossner MJ. Split protein biosensor assays in molecular pharmacological studies. Drug Discov Today 2016 Mar;21(3):415-29.

Wehr MC, Laage R, Bolz U, Fischer TM, Grünewald S, Scheek S, Bach A, Nave K-A, and Rossner MJ. Monitoring regulated protein-protein interactions using split TEV. Nat. Methods 2006 3, 985–993.

Bedenk BT, ..., Deussing JM, ..., Wotjak CT. Mn2+ dynamics in manganese-enhanced MRI (MEMRI): Cav1.2 channel-mediated uptake and preferential accumulation in projection terminals. Neuroimage. 2018 Apr 1;169:374-382

Jurik A, Auffenberg E, Klein S, Deussing JM, Schmid RM, Wotjak CT, Thoeringer CK. Roles of prefrontal cortex and paraventricular thalamus in affective and mechanical components of visceral nociception. Pain. 2015 Aug 6.

Michael J. Ziller et al.: Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell 22, 2018, 559–574

Galonska C*, Ziller MJ*, Karnik R, Meissner A. Ground state conditions induce rapid reorganization of core pluripotency factor binding that precede global epigenetic reprogramming. Cell Stem Cell. 2015 Oct 1;17(4):462-70

Cacchiarelli D*, Trapnell C*, Ziller MJ*, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, Rinn JL, Daley GQ, Meissner A, Lander ES, and Mikkelsen TS. Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency. Cell 2015 Jul 16;162(2):412-24

Ziller MJ, Hansen KD, Meissner A, Aryee MJ. Coverage and replicate requirements for whole genome bisulfite sequencing. Nat Methods 2015 Mar;12(3):230-2

Ziller MJ*, Reuven E*, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov A, Epstein C, Rinn JL, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A, Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature 2015 Feb 19;518(7539):355-9

Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A. Charting a dynamic DNA methylation landscape of the human genome. Nature 2013 Aug 22;500(7463):477-81

Gifford CA*, Ziller MJ*, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A. Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell 2013 May 23;153(5):1149-63

Ziller MJ*, Müller F*, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A. Genomic Distribution and Inter-Sample Variation of non-CpG Methylation Across Human Cell Types. PLoS Genet. 2011 Dec;7(12):e1002389