Previous Faculty Publications

Below you will find a selection of research articles published by members of the IMPRS-TP faculty prior to 2022.

Ruat J, …, Chen A, Czisch M, Wotjak CT. Structural correlates of trauma-induced hyperarousal in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Dec 20;111:110404.

Moore SR, …, Müller-Myhsok B, …, Binder EB, Arloth J. Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation. Transl Psychiatry. 2021 Dec 13;11(1):632.

Oviedo-Salcedo T, …, Falkai P, Hasan A. Cerebrospinal fluid abnormalities in first- and multi-episode schizophrenia-spectrum disorders: impact of clinical and demographical variables. Transl Psychiatry. 2021 Dec 8;11(1):621.

Engelhardt C, …, Chen A, Deussing JM, Schmidt MV. FKBP51 in the Oval Bed Nucleus of the Stria Terminalis Regulates Anxiety-Like Behavior. eNeuro. 2021 Dec 6;8(6):ENEURO.0425-21.2021.

Smigielski L, …, Falkai P, Schulze TG, Grünblatt E. Polygenic risk scores across the extended psychosis spectrum. Transl Psychiatry. 2021 Nov 26;11(1):600.

Klein AS, Dolensek N, Weiand C & Gogolla N. Fear balance is maintained by bodily feedback to the insular cortex in mice. Science 18 Nov 2021. 374 (6570): 1010-1015.

Pagella S, Deussing JM, Kopp-Scheinpflug C. Expression Patterns of the Neuropeptide Urocortin 3 and Its Receptor CRFR2 in the Mouse Central Auditory System. Front Neural Circuits. 2021 Nov 12;15:747472.

Kyrousi C, …, Binder E, …, Cappello S. Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity. Nat Commun. 2021 Nov 2;12(1):6298.

Cruceanu C, …, Cappello S, Theis FJ, Binder EB. Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. Am J Psychiatry. 2021 Oct 26:appiajp202121010095.

Allenmark F, …, Koutsouleris N, Falkai P, …, Falter-Wagner CM. Acquisition and Use of 'Priors' in Autism: Typical in Deciding Where to Look, Atypical in Deciding What Is There. J Autism Dev Disord. 2021 Oct;51(10):3744-3758.

Pelin H, …, Müller-Myhsok B, Andlauer TFM. Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning. Neuropsychopharmacology. 2021 Oct;46(11):1895-1905.

Hühne A, …, Schmidt MV, Rossner MJ, Landgraf D. Circadian gene × environment perturbations influence alcohol drinking in Cryptochrome-deficient mice. Addict Biol. 2021 Oct 20:e13105.

Strube W, …, Falkai P, …, Hasan A. Unstable Belief Formation and Slowed Decision-making: Evidence That the Jumping-to-Conclusions Bias in Schizophrenia Is Not Linked to Impulsive Decision-making. Schizophr Bull. 2021 Sep 23:sbab108.

Brandi ML, …, Schilbach L. Imagery of negative interpersonal experiences influence the neural mechanisms of social interaction. Neuropsychologia. 2021 Sep 17;160:107923.

Häusl AS, …, Deussing JM, …, Chen A, Schmidt MV. The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. Mol Psychiatry. 2021 Jul;26(7):3060-3076.

Brunner C, …, Macé E. Whole-brain functional ultrasound imaging in awake head-fixed mice. Nat Protoc. 2021 Jul;16(7):3547-3571.

Kappelmann N, …, Binder EB, …, Arloth J. Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study. Brain Behav Immun. 2021 Jul;95:256-268.

Barker AJ, Helmbrecht TO, Grob AA, Baier H. Functional, molecular and morphological heterogeneity of superficial interneurons in the larval zebrafish tectum. J Comp Neurol. 2021 Jun;529(9):2159-2175.

Martins-de-Souza D, …, Schmitt A, Falkai P, Turck CW. An overview of the human brain myelin proteome and differences associated with schizophrenia. World J Biol Psychiatry. 2021 Apr;22(4):271-287.

Safaiyan S, …, Rossner MJ, …, Simons M. White matter aging drives microglial diversity. Neuron. 2021 Apr 7;109(7):1100-1117.e10. doi: 10.1016/j.neuron.2021.01.027.

Papiol S, Schmitt A, …, Rossner MJ, Schulze TG, Falkai P. Association Between Physical Activity and Schizophrenia: Results of a 2-Sample Mendelian Randomization Analysis. JAMA Psychiatry. 2021 Apr 1;78(4):441-444.

Filiou MD, Nussbaumer M, Teplytska L, Turck CW. Behavioral and Metabolome Differences between C57BL/6 and DBA/2 Mouse Strains: Implications for Their Use as Models for Depression- and Anxiety-Like Phenotypes. Metabolites. 2021 Feb 23;11(2):128.

Kappelmann N, Arloth J, …, Binder EB. Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study. JAMA Psychiatry. 2021 Feb 1;78(2):161-170.

Koutsouleris N, …, Falkai P et al. Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression. JAMA Psychiatry. 2021 Feb 1;78(2):195-209.

Lopez JP, …, Schmidt MV, Binder EB, Theis FJ, …, Chen A. Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. Sci Adv. 2021 Jan 27;7(5):eabe4497.

Dewald-Kaufmann JF, …, Falkai P, …, Padberg F. Dynamics of the immediate behavioral response to partial social exclusion. Sci Rep. 2021 Jan 20;11(1):1853.

Schneider M, …, Binder EB, Spoormaker VI. Pupil Dilation during Reward Anticipation Is Correlated to Depressive Symptom Load in Patients with Major Depressive Disorder. Brain Sci. 2020 Nov 25;10(12):906.

Karamihalev S, …, Schmidt MV, Chen A. Social dominance mediates behavioral adaptation to chronic stress in a sex-specific manner. Elife. 2020 Oct 9;9:e58723.

Schludi MH, ...Arzberger T and Edbauer D. Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing. Acta Neuropathol. 2015 Oct;130(4):537-55. 

Levin J, Bak TH, Rominger A, Mille E, Arzberger T, Giese A, Ackl N, Lorenzl S, Bader B, Patzig M, Bötzel K, Danek A. The association of aphasia and right-sided motor impairment in corticobasal syndrome. J Neurol. 2015 Jul 5.

Attardo A, Fitzgerald JE and Schnitzer MJ. Impermanence of dendritic spines in live adult CA1 hippocampus. Nature. 2015 Jul 30;523(7562):592-6

Barretto RP, Ko TH, Jung JC, Wang TJ, Capps G, Waters AC, Ziv Y, Attardo A, Recht L, Schnitzer MJ. Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy. Nat Med. 2011 Feb;17(2):223-8.

Attardo A, Fabel K, Krebs J, Haubensak W, Huttner WB, Kempermann G. Tis21 expression marks not only populations of neurogenic precursors but also new postmitotic neurons in adult hippocampal neurogenesis. Cereb Cortex 2010 Feb;20(2):304-14.

Attardo A, Calegari F, Haubensak W, Wilsch-Bräuninger M, and Huttner WB. Live imaging at the onset of cortical neurogenesis reveals differential appearance of the neuronal phenotype in apical versus basal progenitor progeny. PLoS ONE 2008 Jun 11;3(6):e2388

Helmbrecht TO, dal Maschio M, Donovan JC, Koutsouli S & Baier H. Topography of a Visuomotor Transformation. Neuron 100, 1429–1445 December 19, 2018

Larsch J & Baier H. Biological Motion as an Innate Perceptual Mechanism Driving Social Affiliation. Current Biology 28, 3523–3532 November 19, 2018

Bernal Sierra YA, ..., Baier H, ... and Schmitz D.: Potassium channel-based optogenetic silencing. Nature Communications | (2018) 9:4611 | DOI: 10.1038/s41467-018-07038-8 | OPEN access

dal Maschio M, ..., and Baier H: Linking Neurons to Network Function and Behavior by Two-Photon Holographic Optogenetics and Volumetric Imaging. Neuron, May 17 2017, Vol 94, 4, p774–789.e5

Filosa A, Barker AJ, Dal Maschio M and Baier H. Feeding State Modulates Behavioral Choice and Processing of Prey Stimuli in the Zebrafish Tectum. Neuron May 4, 2016: 90, 596–608.

Temizer I, Donovan JC, Baier H, Semmelhack JL. A visual pathway for looming-evoked escape in larval zebrafish. Curr Biol. 2015 Jul 20;25(14):1823-34

Auer TO, Xiao T, Bercier V, Gebhardt C, Duroure K, Concordet JP, Wyart C, Suster M, Kawakami K, Wittbrodt J, Baier H, Del Bene F. Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3. Elife 2015 Jun 15;4.

Kubo F, Hablitzel B, Dal Maschio M, Driever W, Baier H, Arrenberg AB. Functional architecture of an optic flow responsive area that drives horizontal eye movements in zebrafish. Neuron 2014 Mar 19; 81:1344-59.

Ziv L, Muto A, Schoonheim PJ, Meijsing SH, Strasser D, Ingraham HA, Schaaf MJ, Yamamoto KR, Baier H. An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Mol Psychiatry 2013 Jun; 18:681-691.

Xiao T, Staub W, Robles E, Gosse NJ, Cole GJ, Baier H. Assembly of lamina-specific neuronal connections by Slit bound to type IV collagen. Cell 2011 Jul 8; 146:164-176.

Del Bene F, Wyart C, Robles E, Tran A, Looger L, Scott EK, Isacoff EY, Baier H. Filtering of visual information in the tectum by an identified neural circuit. Science 2010 Oct 29; 330:669-673.

Arrenberg AB, Stainier DY, Baier H, Huisken J. Optogenetic control of cardiac function. Science 2010 Nov 12; 330:971-974.

Emeny RT,…, Schmidt MV, …, EB Binder and Ladwig KH.: Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model. Neuropsychopharmacology (2017), 1–12

Halldorsdottir T & Binder EB. Gene × Environment Interactions: From Molecular Mechanisms to Behavior. Annu Rev Psychol. 2016 Sep 30.

Yehuda R, Daskalakis NP, … & Binder EB. Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. Biol Psychiatry. 2016 Sep 1;80(5):372-80

Zannas AS, ..., Binder E and Mehta D. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology Dec 2015, 16:266

Zannas AS, Provençal N, Binder EB.Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions. Biol Psychiatry. 2015 Sep 1;78(5):327-35.

Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron 2015 Jun 3;86(5):1189-202

Pérez-Brangulí F, ..., Cappello S & Winner B. Human SPG11 cerebral organoids reveal cortical neurogenesis impairment. Human Molecular Genetics 2019, ddy397 OPEN ACCESS

Buchsbaum IY, Cappello S: Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro models. Development 2019 146: dev163766.

Schmid MT, Weinandy F., Wilsch-Bräuninger M, Huttner WB, Cappello S and Götz M. The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration. Front Cell Neurosci 2014 Aug 7; 8:2015

Cappello S, Gray MJ, Badouel C, et al. Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt mammalian neuroprogenitor cell proliferation, differentiation and cerebral cortical development. Nature Genetics 2013, 45(11):1300-1308

Stahl R, Walcher T, De Juan Romero C, Pilz GA, Cappello S, Irmler M, Sanz-Aquela JM, Beckers J, Blum R, Borrell V, Götz M. Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate. Cell 2013 Apr 25; 153(3):535-549

Cappello S, Böhringer CR, Bergami M, Conzelmann KK, et al.  A radial glia specific role of RhoA in double-cortex formation. Neuron 2012, 73(5):911-924

Cappello S, Attardo A, Wu X, Iwasato T, Itohara S, et al. The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nature Neuroscience 2006 Sep; 9(9):1099-1117

Engel M, ..., Wotjak CT, Schmidt MV, Deussing JM, Binder EB, Chen A. The Role of m6A/m-RNA Methylation in Stress Response Regulation. Neuron Volume 99, Issue 2, p389–403.e9, 25 July 2018

Ezra-Nevo G, ..., Deussing JM, ... and Chen A. Cerebellar Learning Properties Are Modulated by the CRF Receptor. J of Neurosc. 25 July 2018, 38 (30) 6751-6765

Ramot, A., ... & Chen, A. Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress. Nat Neurosci. 2017 Jan 30. Epub ahead of print

Schroeder M, ...., and Chen A. A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype. Cell Metabolism (2017), http://dx.doi.org/10.1016/j.cmet.2017.05.001

Henckens MJAG, …, Deussing JM, …, and Chen A. CRF receptor type 2 neurons in the posterior bed nucleus of the stria terminalis critically contribute to stress recovery. Molecular Psychiatry (2016) 00, 1–10, Open Acess

Volk N, Pape JC, ... Binder EB & Chen A. Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress. Cell Reports 17, 1882–1891 November 8, 2016

Kuperman Y, Weiss M, Dine J, ..., Deussing J, Eder M and Chen A. CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting. Cell Metabolism June 14, 2016: 23, 1–15; OPEN ACCESS 

Elliott E, Manashirov S, Zwang R, Gil S, Tsoory M and Chen A. Dnmt3a in the medial prefrontal cortex regulates anxiety-like behavior in adult mice. J Neurosci. 2016 Jan 20;36(3):730-40

Issler O, Haramati S, Paul ED, Maeno H, Navon I, Zwang R, Gil S, Mayberg HS, Dunlop BW, Menke A, Awatramani R, Binder EB, Deneris ES, Lowry CA, Chen A. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity. Neuron. 2014 Jul 16;83(2):344-60

Shemesh Y, Sztainberg Y, Forkosh O, Shlapobersky T, Chen A*, Schneidman E*. High-order social interactions in groups of mice. eLife 2013 Sep 3; 2:e00759.

Lebow L, Neufeld-Cohen A, Kuperman Y, Gil S and Chen A. Susceptibility to PTSD is mediated by CRF receptor type 2 levels in the bed nucleus of the stria terminalis. J Neurosci. 2012 May 16; 32:6906-6916.

Shemesh Y, ...Deussing JM, ...& Chen A. Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics. Nature Neuroscience, 2016, doi:10.1038/nn.4346

N Dedic , …, CT Wotjak ,  …, A Chen,  …, MV Schmidt , EB Binder and JM Deussing. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. Molecular Psychiatry (2018) 23, 533–543 OPEN ACCESS 

Dedic N, ..., Wotjak CT, ..., Chen A, Schmidt MV, ..., Deussing JM; Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety; Nature Neuroscience (2018), 21(6):803-807

Metzger MW, ..., Schmidt MV, ..., Chen A, ...& Deussing JM: Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality. J Neurosci 2017, 37 (48) 11688-11700 Open Access Article

Dedic N, … Wotjak CT, … Chen A, … Schmidt MV, Binder EB and Deussing JM. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.
Mol Psychiatry. 2017 Jul 11

Kumar D, , Dedic N, Flachskamm C, Voulé S, Deussing JM and Kimura M. Cacna1c (Cav1.2) Modulates Electroencephalographic Rhythm and Rapid Eye Movement Sleep Recovery. Sleep 2015 Sep 1;38(9):1371-8

Falkai P, Rossner MJ, Schulze TG,Hasan A, Brzózka MM, Malchow B, Honer WG, Schmitt A. Kraepelin revisited: schizophrenia from degeneration to failed regeneration. Mol Psychiatry. 2015 Jun;20(6):671-6

Shi S, Wagner J, Mitteregger-Kretzschmar G, Ryazanov S, Leonov A, Griesinger C and Giese A. Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice. J Neuropathol Exp Neurol. 2015 Sep;74(9):924-33. 

Deeg AA, Reiner AM, Schmidt F, Schueder F, Ryazanov S, Ruf VC, Giller K, Becker S, Leonov A, Griesinger C, Giese A, Zinth W. Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates.  Biochim Biophys Acta. 2015 Sep;1850(9):1884-90.

Gogolla, N. The Insular Cortex. Current Biology, Vol 27/12, 19 June 2017, R580–R586

Gogolla N, Takesian AE, Feng G, Fagiolini M, Hensch TK. Sensory integration in mouse insular cortex reflects GABA circuit maturation. Neuron 2014 Aug 20; 83, 894-905

Hasan A, Guse B, Cordes J, Wölwer W, Winterer G, Gaebel W, Langguth B, Landgrebe M, Eichhammer P, Frank E, Hajak G, Ohmann C, Verde PE, Rietschel M, Ahmed R, Honer WG, Malchow B, Karch S, Schneider-Axmann T, Falkai P, Wobrock T. Cognitive Effects of High-Frequency rTMS in Schizophrenia Patients With Predominant Negative Symptoms: Results From a Multicenter Randomized Sham-Controlled Trial. Schizophr Bull. 2015 Oct 3. pii: sbv142. 

Wobrock T, Guse B, Cordes J, Wölwer W, Winterer G, Gaebel W, Langguth B, Landgrebe M, Eichhammer P, Frank E, Hajak G, Ohmann C, Verde PE, Rietschel M, Ahmed R, Honer WG, Malchow B, Schneider-Axmann T, Falkai P, Hasan A. Left prefrontal high-frequency rTMS for the Treatment of Schizophrenia with Predominant Negative Symptoms – A Sham-controlled, Randomized Multicentre Trial. Biological Psychiatry 2015 Jun; 77(11):979-88

Strube W, Bunse T, Nitsche MA, Wobrock T, Aborowa R, Misewitsch K, Herrmann M, Falkai P, Hasan A. Smoking restores impaired LTD-like plasticity in schizophrenia: a transcranial direct current stimulation study. Neuropsychopharmacology. 2015 Mar;40(4):822-30.

Hasan A, Misewitsch K, Nitsche MA, Gruber O, Padberg F, Falkai P, Wobrock T: Impaired Motor Cortex Responses in Non-Psychotic First-Degree Relatives of Schizophrenia Patients: A Cathodal tDCS Pilot Study. Brain Stimulation, 2013 Sep; 6(5):821-9

Hasan A, Wobrock T, Grefkes C, Labusga M, Levold K, Schneider-Axmann T, Falkai P, Müller H, Klosterkötter J, Bechdolf A (2012): Deficient Inhibitory Cortical Networks in Antipsychotic-Naive Subjects at Risk of Developing First-Episode Psychosis and First-Episode Schizophrenia Patients: A Cross-Sectional Study. Biological Psychiatry 2012 Nov1; 72(9):744-51

Koutsouleris N, Meisenzahl EM, Borgwardt S, Riecher-Rössler A, Frodl T, Kambeitz J, Köhler Y, Falkai P, Möller HJ, Reiser M, Davatzikos CIndividualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers. Brain. 2015 Jul;138(Pt 7):2059-73. 

Kambeitz J, Kambeitz-Ilankovic L, Leucht S, Wood S, Davatzikos C, Malchow B, Falkai P, Koutsouleris N.Detecting neuroimaging biomarkers for schizophrenia: a meta-analysis of multivariate pattern recognition studies. Neuropsychopharmacology 2015 Jun;40(7):1742-51

Koutsouleris N, Riecher-Rössler A, Meisenzahl EM, Smieskova R, Studerus E, Kambeitz-Ilankovic L, von Saldern S, Cabral C, Reiser M, Falkai P, Borgwardt S.. Detecting the psychosis prodrome across high-risk populations using neuroanatomical biomarkers. Schizophr Bull. 2015 Mar;41(2):471-82.

Kambeitz-Ilankovic L, Meisenzahl EM, Cabral C, von Saldern S, Kambeitz J, Falkai P, Möller HJ, Reiser M, Koutsouleris N. Prediction of outcome in the psychosis prodrome using neuroanatomical pattern classification. Schizophr Res. 2015 Mar 26. pii: S0920-9964(15)00134-6.

Wei H, Landgraf D, Wang G, McCarthy MJ. Inositol polyphosphates contribute to cellular circadian rhythms: Implications for understanding lithium's molecular mechanism. Cell Signal. 2018 Jan 11;44:82-91

Mende M, Fletcher EV, Belluardo JL et al. Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron June 15, 2016: vol90/6, p1189–1202

Schormair B., ..., Müller-Myhsok B. & Winkelmann J.: Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis. Lancet Neurol 2017; 16: 898–907

Andlauer TFM, … Binder EB, ... and Müller-Myhsok B. Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Sci Adv 2016 (June 17), 2.

Brenndörfer J, Altmann A, Widner-Andrä R, Pütz B, Czamara D, Tilch E, Kam-Thong T, Weber P, Rex-Haffner M, Bettecken T, Bultmann A, Müller-Myhsok B, Binder EE, Landgraf R, Czibere L. Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice. PLoS One. 2015 May 26;10(5):e0128465.

Uher R, Ripke S, Müller-Myhsok B, Lewis CM, Perlis RH. Association of a brain methylation site with clinical outcomes in depression does not replicate across populations. Am J Psychiatry. 2015 Apr;172(4):395-7.

Palm U, Keeser D, Hasan A, ...Falkai P, ..., and Padberg F. Prefrontal Transcranial Direct Current Stimulation for Treatment of Schizophrenia With Predominant Negative Symptoms: A Double-Blind, Sham-Controlled Proof-of-Concept Study. Schizophr Bull. 2016 Apr 20. pii: sbw041

Jobst A, Brakemeier E-L, ...Falkai P, ....and Padberg F. European Psychiatric Association Guidance on psychotherapy in chronic depression across Europe. European Psychiatry 2016, 33: 18–36 

Levkovitz Y., Isserles M., Padberg F., et al.Efficacy and safety of deep transcranial magnetic stimulation for major depression: a prospective multicenter randomized controlled trial. World Psychiatry 2015;14:64–73 

Wehr MC, Holder M, Maile T, Saunders R, Jiang M, Instrell R, Howell M, Rossner MJ, Tapon N. Saltinducible kinases regulate growth through the Hippo signalling pathway. Nat Cell Biol, 2013 Jan; 15, 61–71.

Brzózka MM, Rossner MJ. Deficits in trace fear memory in a mouse model of the schizophrenia risk gene TCF4. Beh Brain Res., 2013 Jan 15; 237:348-56

Brankatschk B, Wichert SP, Schaad O, Rossner MJ, Jean Gruenberg. Regulation of the EGF transcriptional response by endocytic sorting. Science Sig, 2012 Mar 13;5(215):ra21

Fledrich R, Schlotter-Weigel B, Schnizer T, Wichert SP, Stassart RM, Meyer zu Horste G, Weiss BG, Haag U, C. Walter M, Rautenstrauss B, Paulus, W, Rossner MJ and Sereda MW. A rat model of CMT1A recapitulates disease variability and supplies biomarkers of axonal loss in patients. Brain, 2012 Jan; 135:72-87.

Brzózka MM, Radyushkin R, Wichert SP, Ehrenreich H and Rossner MJ. Cognitive and sensorimotor gating impairments in transgenic mice overexpressing the schizophrenia susceptibility gene Tcf4 inthe forebrain. Biol Psychiatry. 2010 July; 68(1): 33-40.

Bolis D & Schilbach L: ‘I Interact Therefore I Am’: The Self as a Historical Product of Dialectical Attunement. Topoi, Springer 2018, OpenAccess

Prellera KH, Schilbach L, ... and Vollenweider FX: Role of the 5-HT2A receptor in self- and other-initiated social interaction in LSD-induced states — a pharmacological fMRI study. J. Neurosci ; 10.1523/JNEUROSCI.1939-17.2018

Bolis D & Schilbach L. Observing and participating in social interactions: Action perception and action control across the autistic spectrum.  Dev Cog Neuro (2017) S1878-9293(16)30174-8 Online Ahead of Print - Open Access

Bolis, D., Balsters, J., Wenderoth, N., Becchio, C., & Schilbach, L. Beyond autism: Introducing the dialectical misattunement hypothesis and a Bayesian account of intersubjectivity. ©S. Karger AG, Psychopathology; 2017; 50 (6): 355-372

Sevgi M, Diaconescu A, Tittgemeyer M & Schilbach L. Social Bayes: Using Bayesian Modeling to Investigate Autistic Trait-Related Differences in Implicit Social Cognition. Biol Psychiatry. 2015 Dec 9. pii: S0006-3223(15)01035-5

Schilbach L. Toward a second-person neuropsychiatry. Philos Trans R Soc Lond B Biol Sci. 2016 Jan 19;371(1686):20150081

Schilbach L*, Hoffstaedter F*, et al. Transdiagnostic similarities and differences in resting state functional connectivity in schizophrenia and depression. Neuroimage Clin. 2015 Dec 2;10:326-35

Mulej Bratec S, Xie X, Wang Y, Schmid G, Schilbach L, Zimmer C, Wohlschläger A, Riedl V, Sorg C. Cognitive emotion regulation anhances aversive prediction error activity while reducing emotional responses. Neuroimage. 2015 Dec;123:138-48

Sevgi M, Rigoux LY, Kühn A, Mauer J, Schilbach L, Hess ME, Gründler TOJ, Ullsperger M, Stephan KE, Brüning JC, Tittgemeyer M. An Obesity-Predisposing Genetic Variant of the FTO Gene Regulates D2R-Dependent Reward Learning. J Neurosci. 2015 Sep 9;35(36):12584-92

Schilbach L, Müller V, Hoffstaedter F, Clos M, Goya-Maldonado R, Gruber O, Eickhoff SB. Meta-analytically informed network analysis of resting state fMRI data reveals hyperconnectivity in individuals with depression. PLoS One 2014 Apr 23;9(4):e94973.

Pöhlmann ML et al and Schmidt MV (2018): Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs.  Front. Behav. Neurosci. 12:262

G. Balsevich, A.S. Häusl, C.W. Meyer, S. Karamihalev, ..., A. Chen, ... & M.V. Schmidt: Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. Nature communications | 2017, 8: 1725 | Open Access Article

Hartmann J, ..., Chen A, Joëls M, Deussing JM and Schmidt MV. Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor.
Mol. Psych. adv. online pub. 31 May 2016; doi: 10.1038/mp.2016.87 OPEN ACCESS

Uribe-Mariño A, …, Chen A, Deussing JM and Schmidt MV. Prefrontal cortex corticotropin-releasing factor receptor 1 conveys acute stress-induced executive dysfunction. Biol. Psych. Nov 15 2016, Vol 80, Iss 10, Pages 743–753

Santarelli S, Namendorf C, Anderzhanova E, Gerlach T, Bedenk B, Kaltwasser S, Wagner K, Labermaier C, Reichel J, Drgonova J, Czisch M, Uhr M, Schmidt MV. The amino acid transporter SLC6A15 is a regulator of hippocampal neurochemistry and behavior. J Psychiatr Res. 2015 Sep;68:261-9.

Balsevich G, Baumann V, Uribe A, Chen A and Schmidt MV. Prenatal Exposure to Maternal Obesity Alters Anxiety and Stress Coping Behaviors in Aged Mice. Neuroendocrinology. 2015 Aug 7

Kohl C, Wang XD, Grosse J, Fournier C, Harbich D, Westerholz S, Li JT, Bacq A, Sippel C, Hausch F, Sandi C, Schmidt MV. Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice. Psychoneuroendocrinology 2015 May;55:128-43.

Wagner KV, Hartmann J, Labermaier C, Häusl AS, Zhao G, Harbich D, Schmid B, Wang XD, Santarelli S, Kohl C, Gassen NC, Matosin N, Schieven M, Webhofer C, Turck CW, Lindemann L, Jaschke G, Wettstein JG, Rein T, Müller MB, Schmidt MV. Homer1/mGluR5 activity moderates vulnerability to chronic social stress. Neuropsychopharmacology. 2015 Mar 13;40(5):1222-33

Hartmann J, ..., Chen A, Joëls M, Deussing JM and Schmidt MV. Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor.
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Schmitt A, Turck C.W, Pilz PK, Malchow B, von Wilmsdorff M, Falkai P, Martins-de Souza D. Proteomic similarities between heterozygous reeler mice and schizophrenia. Biol Psychiatry 2013; 74 (6): e5-e10

Iwata K, Cafe-Mendes CC, Schmitt A, Manabe T, Matsuzaki H, Falkai P, Turck CW, Martins-de-Souza D. The human oligodendrocyte protein. Proteomics 2013 Dec; 13 (23-24):3548-3553

Kao PF, Banigan MG, Kozubek JA, Winslow AR, Medina J, Costa J, Schmitt A, Schneider A, Cabral H, Vanderburg CR, and Delalle I. Differential expression ofexosomal miRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. PLoSONE 2013; 8(1): e48814

Giaccone G, Arzberger T, Alafuzoff I, Al-Sarraj S, Budka H, Duyckaerts C, Falkai P, Ferrer I, Ironside JW, Kovacs GG, Parchi P, Patsouris E, Revesz T, Riederer P, Rozemuller A, Schmitt A, Winblad B, Kretzschmar H.; BrainNet Europe consortium. New lexicon and criteria for the diagnosis of Alzheimer’s disease. Lancet Neurology 2011 Apr: 10(4): 298-299

Schmitt A, Steyskal C, Bernstein HG, Parlapani E, Schaeffer EL, Gattaz WF, Bogerts B, Schmitz C, Falkai P. Stereologic investigation of the posterior part of the hippocampus in schizophrenia. Acta Neuropathologica 2009 Apr: 117 (4): 395-407

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Ballnus B., … and Theis FJ.: Comprehensive benchmarking of Markov chain Monte Carlo methods for dynamical systems. BMC Systems Biology (07/2017) 11:63

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Park D, ... and Turck CW. Delineation of molecular pathway activities of the chronic antidepressant treatment response suggests important roles for glutamatergic and ubiquitin proteasome systems. Translational Psychiatry (2017) 7, e1078

Weckmann K, Labermaier C, Asara JM, Müller MB, Turck CW. Time-dependent metabolomic profiling of Ketamine drug action reveals hippocampal pathway alterations and biomarker candidates. Transl Psychiatry 2014 Nov 11: 4:e481.

He Y, Hogrefe CE, Grapov D, Palazoglu M, Fiehn O, Turck CW, Golub MS. Identifying individual differences of fluoxetine response in juvenile rhesus monkeys by metabolite profiling. Transl Psychiatry 2014 Nov 4; 4:e478.

Ditzen C, Tang N, Jastorff AM, Teplytska L, Yassouridis A, Maccarrone G, Uhr M, Bronisch T, Miller CA, Holsboer F, Turck CW. Cerebrospinal fluid biomarkers for major depression confirm relevance of associated pathophysiology.Neuropsychopharmacology 2012 Mar;37(4):1013-25

Webhofer C, Gormanns P, Tolstikov V, Zieglgänsberger W, Sillaber I, Holsboer F, Turck CW. Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation. Transl Psychiatry 2011 Dec 13; 1: e58

Ditzen, C, Varadarajulu, J, Czibere, L, Gonik, M, Targosz, BS, Hambsch, B, Bettecken, T, Keßler MS, Frank, E, Bunck, M, Teplytska, L, Erhardt, A, Holsboer, F, Müller-Myhsok, B, Landgraf, R, Turck, CW. Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways. Mol Psychiatry 2010 Jul; 15(7):702-711.

Vogl AM, Brockmann MM, Giusti SA, Maccarrone G, Vercelli CA, Bauder CA, Richter JS, Roselli F, Hafner AS, Dedic N, Wotjak CT, Vogt-Weisenhorn DM, Choquet D, Turck CW, Stein V, Deussing JM, Refojo D.. Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition. Nat Neurosci. 2015 Feb;18(2):239-51

Wintgens JP, Rossner MJ, Wehr MC. Characterizing Dynamic Protein-Protein Interactions Using the Genetically Encoded Split Biosensor Assay Technique Split TEV. Methods Mol Biol. 2017;1596:219-238

Wehr MC and Rossner MJ. Split protein biosensor assays in molecular pharmacological studies. Drug Discov Today 2016 Mar;21(3):415-29.

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Jurik A, Auffenberg E, Klein S, Deussing JM, Schmid RM, Wotjak CT, Thoeringer CK. Roles of prefrontal cortex and paraventricular thalamus in affective and mechanical components of visceral nociception. Pain. 2015 Aug 6.

Michael J. Ziller et al.: Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell 22, 2018, 559–574

Galonska C*, Ziller MJ*, Karnik R, Meissner A. Ground state conditions induce rapid reorganization of core pluripotency factor binding that precede global epigenetic reprogramming. Cell Stem Cell. 2015 Oct 1;17(4):462-70

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Ziller MJ, Hansen KD, Meissner A, Aryee MJ. Coverage and replicate requirements for whole genome bisulfite sequencing. Nat Methods 2015 Mar;12(3):230-2

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Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A. Charting a dynamic DNA methylation landscape of the human genome. Nature 2013 Aug 22;500(7463):477-81

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