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Speaker: Dr. Elizabeth A. Heller

Chromatin-directed alternative splicing in brain reward regions

Munich Psychiatry Lecture Series | MPLS
Regulation of gene expression via stably altered chromatin is a compelling area of study for highly heritable neuropsychiatric diseases, such as addiction (Walker, Cates, Heller, & Nestler, 2015). However, due to the promiscuous nature of chromatin-remodeling factors (Kennedy et al., 2013; Maze et al., 2011), previous studies have largely failed to distinguish between the mere presence and the functional relevance of drug-induced histone post-translational modifications (HPTMs). [more]
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